Neoadjuvant therapies for hepatocellular carcinoma before liver transplantation: A critical appraisal
نویسندگان
چکیده
منابع مشابه
Liver Transplantation for Hepatocellular Carcinoma: An Appraisal of Current Controversies
Cost-effective and efficacious approaches to the management of hepatocellular carcinoma (HCC) must be developed in response to the rising incidence of this disease worldwide. While surgical resection is the current standard of care, most patients afflicted with HCC are unresectable at diagnosis. Developing good therapy for these patients is thus imperative. Liver transplantation offers the poss...
متن کاملLiver transplantation for hepatocellular carcinoma.
Liver transplantation has become the best option in patients with decompensated cirrhosis and a small hepatocellular carcinoma. Indeed, because of the severity of cirrhosis, resection is usually impossible and in addition, transplantation provides survival rates close to those obtained in cirrhotic patients without malignancy (70 to 80% 3-year survival rate). In patients with a small hepatocell...
متن کاملLiver transplantation for hepatocellular carcinoma.
In patients with cirrhosis and hepatocellular carcinoma (HCC), orthotopic liver transplantation (OLT) offers hope for cure of both the complicating HCC and the underlying chronic liver disease. Excellent 5 year survival has been reported when the restrictive Milan criteria are used to select transplant candidates. Alternative recommendations have recently been proposed by groups at University o...
متن کاملLiver transplantation for hepatocellular carcinoma.
BACKGROUND The treatment of hepatocellular carcinoma (HCC) is challenging, but transplantation of the liver has emerged as one of the options in the therapeutic armamentarium against this disease. METHODS This article reviews the changing criteria for patient eligibility for liver transplantation for HCC and presents an initial evaluation of institutional treatment outcomes for this treatment...
متن کاملLiver transplantation for hepatocellular carcinoma.
Hepatitis B is endemic in many regions of Asia, including China, Korea and India. This results in a heavy burden of hepatocellular carcinoma (HCC) because hepatitis B virus is a major risk factor in the development of the disease. In addition, the incidence of hepatitis-C-related HCC is on the rise in the United States. HCC patients with poor liver function reserve are not suitable candidates f...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2006
ISSN: 1527-6465,1527-6473
DOI: 10.1002/lt.21018